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KMID : 1146220230310020098
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Journal of Cardiovascular Imaging
2023 Volume.31 No. 2 p.98 ~ p.104
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Changes in Cardiac Structure and Function After Kidney Transplantation: A New Perspective Based on Strain Imaging
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Kim Da-Rae
Kim Min-Jeong
Park Jae-Berm
Lee Ju-Han
Huh Kyu-Ha
Hong Geu-Ru
Ha Jong-Won
Choi Jin-Oh
Shim Chi-Young
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Abstract
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BACKGROUND : We aimed to investigate left ventricular (LV) global longitudinal strain (GLS) in end-stage renal disease patients and its change after kidney transplantation (KT).
METHODS : We retrospectively reviewed patients who underwent KT between 2007 and 2018 at two tertiary centers. We analyzed 488 patients (median age, 53 years; 58% male) who had obtained echocardiography both before and within 3 years after KT. Conventional echocardiography and LV GLS assessed by two-dimensional speckle-tracking echocardiography were comprehensively analyzed. Patients were classified into three groups according to the absolute value of pre-KT LV GLS (|LV GLS|). We compared longitudinal changes of cardiac structure and function according to pre-KT |LV GLS|.
RESULTS : Correlation between pre-KT LV EF and |LV GLS| were statistically significant, but the constant was not high (r = 0.292, p < 0.001). |LV GLS| was widely distributed at corresponding LV EF, especially when the LV EF was > 50%. Patients with severely impaired pre-KT |LV GLS| had significantly larger LV dimension, LV mass index, left atrial volume index, and E/e’ and lower LV EF, compared to mildly and moderately reduced pre-KT |LV GLS|. After KT, the LV EF, LV mass index, and |LV GLS| were significantly improved in three groups. Patients with severely impaired pre-KT |LV GLS| showed the most prominent improvement of LV EF and |LV GLS| after KT, compared to other groups.
CONCLUSIONS : Improvements in LV structure and function after KT were observed in patients throughout the full spectrum of pre-KT |LV GLS|.
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KEYWORD
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Left ventricle, Global longitudinal strain, Kidney transplantation
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